Chronic treatment with terbutaline increases glucose and oleic acid oxidation and protein synthesis in cultured human myotubes

by Christine Skagen, Tuula A. Nyman, Xiao-Rong Peng, Gavin O'Mahony, Eili Tranheim Kase, Arild Chr Rustan, G. Hege Thoresen
Published 2021-01-01

A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes

by Se-Hyung Park, Robert N. Helsley, Leila Noetzli, Ho-Chou Tu, Kristina Wallenius, Gavin O’Mahony, Jeremie Boucher, Jianming Liu, Samir Softic
Published 2021-09-01

PPARγ and PPARα synergize to induce robust browning of white fat in vivo

by Tobias Kroon, Matthew Harms, Stefanie Maurer, Laurianne Bonnet, Ida Alexandersson, Anna Lindblom, Andrea Ahnmark, Daniel Nilsson, Peter Gennemark, Gavin O'Mahony, Victoria Osinski, Coleen McNamara, Jeremie Boucher
Published 2020-06-01

Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects.

by Dustin K Bauknight, Victoria Osinski, Siva Sai Krishna Dasa, Anh T Nguyen, Melissa A Marshall, Julia Hartman, Matthew Harms, Gavin O'Mahony, Jeremie Boucher, Alexander L Klibanov, Coleen A McNamara, Kimberly A Kelly
Published 2019-01-01

The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells

by Abel M. Mengeste, Jenny Lund, Parmeshwar Katare, Roya Ghobadi, Hege G. Bakke, Per Kristian Lunde, Lars Eide, Gavin O’ Mahony, Sven Göpel, Xiao-Rong Peng, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan
Published 2021-01-01