Short Chain Fatty Acids Effect on Chloride Channel ClC-2 as a Possible Mechanism for Lubiprostone Intestinal Action

by Marcelo A. Catalán, Francisca Julio-Kalajzić, María Isabel Niemeyer, Luis Pablo Cid, Francisco V. Sepúlveda
Published 2020-07-01

Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filter.

by Leandro Zúñiga, Valeria Márquez, Fernando D González-Nilo, Christophe Chipot, L Pablo Cid, Francisco V Sepúlveda, María Isabel Niemeyer
Published 2011-01-01

Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K+ Channel.

by Sandra Villanueva, Johanna Burgos, Karen I López-Cayuqueo, Ka-Man Venus Lai, David M Valenzuela, L Pablo Cid, Francisco V Sepúlveda
Published 2015-01-01

Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish.

by Isabel Cornejo, Olga Andrini, María Isabel Niemeyer, Vanessa Marabolí, F Danilo González-Nilo, Jacques Teulon, Francisco V Sepúlveda, L Pablo Cid
Published 2014-09-01

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine

by David Ramírez, Mauricio Bedoya, Aytug K. Kiper, Susanne Rinné, Samuel Morales-Navarro, Erix W. Hernández-Rodríguez, Francisco V. Sepúlveda, Niels Decher, Wendy González
Published 2019-05-01

Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K₂P Channels

by Daniel Bustos, Mauricio Bedoya, David Ramírez, Guierdy Concha, Leandro Zúñiga, Niels Decher, Erix W. Hernández-Rodríguez, Francisco V. Sepúlveda, Leandro Martínez, Wendy González
Published 2020-01-01

Tissue Distribution of Kir7.1 Inwardly Rectifying K+ Channel Probed in a Knock-in Mouse Expressing a Haemagglutinin-Tagged Protein

by Isabel Cornejo, Sandra Villanueva, Sandra Villanueva, Johanna Burgos, Johanna Burgos, Karen I. López-Cayuqueo, Karen I. López-Cayuqueo, Régine Chambrey, Francisca Julio-Kalajzić, Neudo Buelvas, María I. Niemeyer, Dulce Figueiras-Fierro, Peter D. Brown, Francisco V. Sepúlveda, L. P. Cid
Published 2018-04-01