TCR affinity for self-ligands influences the development and function of encephalitogenic T cells.

by Jianwei Li, Omar Vandal, Derek B Sant'Angelo
Published 2011-03-01

A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.

by Damian Kovalovsky, Mark Pezzano, Benjamin D Ortiz, Derek B Sant'Angelo
Published 2010-01-01

Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.

by Masako Osada, Varan J Singh, Kenmin Wu, Derek B Sant'Angelo, Mark Pezzano
Published 2013-01-01

Selective depletion of eosinophils or neutrophils in mice impacts the efficiency of apoptotic cell clearance in the thymus.

by Hye-Jung Kim, Eric S Alonzo, Guillaume Dorothee, Jeffrey W Pollard, Derek B Sant'Angelo
Published 2010-07-01

Histone deacetylase 3 is required for iNKT cell development

by Puspa Thapa, Sinibaldo Romero Arocha, Ji Young Chung, Derek B. Sant’Angelo, Virginia Smith Shapiro
Published 2017-07-01

The differentiation of ROR-γt expressing iNKT17 cells is orchestrated by Runx1

by Puspa Thapa, Bryce Manso, Ji Young Chung, Sinibaldo Romera Arocha, Hai-Hui Xue, Derek B. Sant’ Angelo, Virginia Smith Shapiro
Published 2017-08-01

Ectopic T cell receptor-α locus control region activity in B cells is suppressed by direct linkage to two flanking genes at once.

by Stefan Knirr, Janette Gomos-Klein, Blanca E Andino, Faith Harrow, Karl F Erhard, Damian Kovalovsky, Derek B Sant'Angelo, Benjamin D Ortiz
Published 2010-11-01

Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.

by Maggie Eidson, Justin Wahlstrom, Aimee M Beaulieu, Bushra Zaidi, Steven E Carsons, Peggy K Crow, Jianda Yuan, Jedd D Wolchok, Bernhard Horsthemke, Dagmar Wieczorek, Derek B Sant'Angelo
Published 2011-01-01